(E)-1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
4-hydroxyderricin
CAS: 55912-03-3
Molecular Formula: C21H22O4
(E)-1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one - Names and Identifiers
| Name | 4-hydroxyderricin |
| Synonyms | hydroxyderricin 4-hydroxyderricin Derricin Impurity 1 2',4-Dihydroxy-3'-(3-methyl-2-butenyl)-4'-methoxy-trans-chalcone (E)-1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one 2-Propen-1-one, 1-[2-hydroxy-4-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)- |
| CAS | 55912-03-3 |
(E)-1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one - Physico-chemical Properties
| Molecular Formula | C21H22O4 |
| Molar Mass | 338.4 |
| Density | 1.181±0.06 g/cm3(Predicted) |
| Melting Point | 136.0-137.0 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| Boling Point | 542.0±50.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Yellow powder |
| pKa | 7.83±0.40(Predicted) |
| Storage Condition | -20°C |
(E)-1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one - Reference Information
| biological activity | 4-Hydroxyderricin is one of the main active ingredients of Angelica sinensis, A selective MAO-B (monoamine oxidase inhibitor) inhibitor with an IC50 of 3.43 μm. 4-Hydroxyderricin can slightly inhibit DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity. |
| Target | IC50: 3.43 μm (MAO-B) |
Last Update：2024-04-09 21:49:45
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Product Name: 4-hydroxyderricin Visit Supplier Webpage Request for quotationCAS: 55912-03-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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